When dealing with health problems it’s important to know how severe the disease is. Knowing this drives a series of treatment decisions, which may improve the symptoms, and in many cases even cure the disease. When the condition’s level of aggressiveness is unknown, a traditionally beneficial treatment may instead cause harm.
The aggressiveness of prostate cancer is hard to determine. Traditionally, physicians have used the prostate-specific antigen (PSA) level, a physical exam, and other methods to estimate the level of prostate cancer to help guide treatment decisions. These are helpful, but they cannot fully determine whether a man has low-risk prostate cancer, which can be managed with active surveillance, or whether he has aggressive prostate cancer, that should be treated immediately.
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